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KMID : 0191120120270030313
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Journal of Korean Medical Science
2012 Volume.27 No. 3 p.313 ~ p.316
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Post-influenza Pneumonia Caused by the USA300 Community-Associated Methicillin-Resistant Staphylococcus aureus in Korea
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Sohn Kyung-Mok
Chung Doo-Ryeon
Baek Jin-Yang
Kim So-Hyun
Joo Eun-Jeong
Ha Young-Eun
Ko Kwan-Soo
Kang Cheol-In
Peck Kyong-Ran
Song Jae-Hoon
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Abstract
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Panton-Valentine leukocidin (PVL)-positive USA300 clone has been the most successful community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) clone spreading in North America. In contrast, PVL-negative ST72-CA-MRSA has been predominant in Korea, and there has been no report of infections by the USA300 strain except only one case report of perianal infection. Here, we describe the first case of pneumonia caused by the USA300 strain following pandemic influenza A (H1N1) in Korea. A 50-year-old man was admitted with fever and cough and chest radiograph showed pneumonic consolidation at the right lower lung zone. He received a ventilator support because of respiratory failure. PCR for pandemic influenza A (H1N1) in nasopharyngeal swab was positive, and culture of sputum and endotracheal aspirate grew MRSA. Typing of the isolate revealed that it was PVL-positive, ST 8-MRSA-SCCmec type IV. The analysis of the PFGE patterns showed that this isolate was the same pulsotype as the USA300 strain.
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KEYWORD
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Influenza, Human, Methicillin-Resistant Staphylococcus aureus, Pneumonia
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